Overexpression of HMGB2 is associated with tumor aggressiveness and prognosis of hepatocellular carcinoma Running title: HMGB2 overexpression in hepatocellular carcinoma
نویسندگان
چکیده
Jung-Hee Kwon, Jongmin Kim, Jin Young Park, Sun Mi Hong, Chang Wook Park , Seok Joo Hong, Sun Young Park, Yoon Jung Choi, In-Gu Do, Jae-Won Joh, Dae Shick Kim, Kwan Yong Choi Department of Life Science, Pohang University of Science and Technology, Pohang 790-784, Korea; CbsBioscience, Inc., 59-5 Jang-Dong, Yuseong-gu, Daejeon 305-343, Korea; Department of Pathology, National Health Insurance Corporation Ilsan Hospital, Goyang-city, Gyeonggi-do 410-719, Korea; Department of Pathology, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea
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rexpression of High-Mobility Group Box 2 Is Associated Tumor Aggressiveness and Prognosis of R atocellular Carcinoma
Downloa pose: We investigated the expression of high-mobility group box 2 (HMGB2) in patients with ocellular carcinoma (HCC) and its clinical effects with underlying mechanisms. erimental Design: HMGB2 mRNA levels were measured in 334 HCC patients by real-time reverse ription-PCR and HMGB2 protein levels in 173 HCC patients by immunohistochemical studies. The B2 expression levelwasmeasured byWe...
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